1 Comprehensive CLIA Test Menu

1.1 Tumor Biomarkers

Biomarker (English)	Clinical Value
CA125	Key marker for ovarian cancer; may increase in endometriosis and pelvic inflammation.
CA15-3	Mainly used in breast cancer monitoring; may also elevate in lung and ovarian cancers.
CA19-9	Sensitive marker for pancreatic and biliary tract cancers.
CA72-4	Auxiliary marker for gastric and ovarian cancers.
CA242	Marker for pancreatic and colorectal cancers, with higher specificity.
CEA	Common marker for colorectal and pancreatic cancers; may elevate in smokers.
CYFRA21-1	Monitoring marker for non-small cell lung cancer (especially squamous cell carcinoma).
SCC	Marker for squamous cell carcinomas (e.g., cervical cancer, lung squamous cancer).
proGRP	Specific marker for small cell lung cancer.
NSE	Marker for small cell lung cancer and neuroendocrine tumors.
HE4	Sensitive marker for ovarian cancer; combined with CA125 for early detection.
CA50	Auxiliary marker for pancreatic, gastric, and other digestive system cancers.
AFP	Important marker for hepatocellular carcinoma and germ cell tumors.
TK1	Reflects cell proliferation; useful in tumor progression monitoring.
PGI	Marker for gastric mucosal function and atrophic gastritis.
PG II	Marker for gastric mucosal function and atrophic gastritis.
G-17	Reflects gastric acid secretion; used for gastric function assessment.
TPSA	Marker for prostate cancer and benign prostatic hyperplasia.
FPSA	Used with TPSA to differentiate prostate cancer from benign disease.
KL-6	Marker for interstitial lung diseases.
VEGF	Reflects tumor angiogenesis; also related to retinal diseases.
MMP-3	Associated with rheumatoid arthritis and tumor invasiveness.

1.2 Cardiovascular Biomarkers

Biomarker (English)	Clinical Value
H-FABP	Sensitive marker for early myocardial injury.
Lp-PLA2	Predictor of atherosclerosis and cardiovascular risk.
hs-cTnT	Gold standard marker for myocardial infarction.
CK-MB	Marker for myocardial injury; less specific than troponins.
MYO	Early sensitive marker of myocardial injury but lacks specificity.
NT-ProBNP	Key marker for diagnosis and prognosis of heart failure.
BNP	Key marker for diagnosis and prognosis of heart failure.
D-Dimer	Marker of thrombosis and fibrinolysis; useful for excluding venous thromboembolism.

1.3 Inflammatory Biomarkers

Biomarker (English)	Clinical Value
PCT	Marker for bacterial infection and sepsis.
SAA	Acute-phase protein for inflammation monitoring.
IL-6	Cytokine involved in infection and immune response.
FR-CRP	Marker for inflammation and cardiovascular risk prediction.
HBP	Early diagnostic and prognostic marker for sepsis and severe infections.

1.4 Thyroid Function Biomarkers

Biomarker (English)	Clinical Value
FT3	Reflects thyroid activity.
FT4	Used to evaluate thyroid function.
TT3	Influenced by plasma protein binding; reflects thyroid function.
TT4	Commonly used for thyroid disease screening.
TSH	Most sensitive marker of thyroid function.
TG	Used for post-thyroid cancer monitoring and thyroid reserve assessment.
TGAb	Autoimmune marker, common in Hashimoto's thyroiditis.
TPOAb	Marker for autoimmune thyroid diseases.
PTH	Assesses calcium and phosphorus metabolism; guides diagnosis of bone metabolic disorders.
TMA	Elevated in autoimmune thyroid diseases.
TRAb	Specific marker for Graves' disease.
TBG	Affects total thyroid hormone measurement.
rT3	Inactive thyroid hormone.

1.5 Other Key Biomarker Categories

Category	Key Biomarkers	Clinical Value Overview
Renal Function	Cystatin C (Cys-C), β2-Microglobulin (β2-MG), Neutrophil Gelatinase-Associated Lipocalin (NGAL), Microalbumin (mAlb)	Early detection of renal injury; more sensitive than traditional markers (e.g., creatinine).
Glucose Metabolism	Insulin (INS), C-Peptide (C-P), Adiponectin (ADPN), Pro-Insulin	Evaluates pancreatic function and insulin resistance; aids in diabetes diagnosis and management.
Anemia	Ferritin (Fer), Transferrin (TRF), Vitamin B12 (VB12)	Assesses iron storage and vitamin deficiency; guides anemia diagnosis and treatment.
Hypertension	Aldosterone (ALD), Renin, Cortisol, Adrenocorticotropic Hormone (ACTH), Angiotensin I/II (A I/A II)	Evaluates adrenal cortex function and RAAS system activity; assists in diagnosing secondary hypertension.
Hepatic Fibrosis	Laminin (LN), Hyaluronic Acid (HA), Type III Procollagen (PIII), Type IV Collagen (CIV), Glycocholic Acid (CG)	Monitors liver fibrosis progression; aids in chronic liver disease management.
Sexual Hormones	FSH, LH, E2, Progesterone (PROG), Prolactin (PRL), Testosterone (TESTO), β-HCG, AMH	Evaluates ovarian/reserve function, male fertility, and pregnancy status; assists in reproductive disorder diagnosis.
Bone Metabolism	25-Hydroxyvitamin D (25-OH-VD), Osteocalcin (OCN), Calcitonin (CT)	Assesses bone health and calcium metabolism; guides osteoporosis prevention and treatment.
Neuro Biomarkers	AD7c-NTP, S100β	Early detection of neuronal damage (e.g., Alzheimer's disease) and brain injury.
Autoimmune Diseases	IgE, IgG4, Anti-CCP, Rheumatoid Factor (RF), Anti-β2-GPI Antibodies (IgM/IgA/IgG)	Diagnoses and monitors autoimmune diseases (e.g., rheumatoid arthritis, IgG4-related diseases).
Infectious Diseases	HBsAg, Anti-HBs, HBeAg, Anti-HBe, Anti-HBc, Anti-HCV, HIV Combo, Anti-TP	Screens for hepatitis B/C, HIV, syphilis, and other infectious diseases.
Growth & Development	Growth Hormone (GH), IGF-1, IGFBP-3	Evaluates growth and metabolic function; aids in diagnosing growth disorders.

2 Market Recognition & Application Cases

2.1 Customer Coverage

Hospitals	Covers 30% of tertiary hospitals in China (over 800 hospitals), including Huashan Hospital, Nanjing Drum Tower Hospital (4300 beds), The First Affiliated Hospital of Zhengzhou University, and over 100 children’s hospitals (e.g., National Children’s Medical Center).
Third-Party Labs	Strategic partnership with KingMed Diagnostics and Dian Diagnostics (both CAP and ISO15189 certified); 50% of KingMed’s 49 laboratories use Norman’s CLIA analyzers and reagents.
Regional Coverage	Cooperates with 85% of tertiary hospitals in Nanjing (27+) and 50% in Jiangsu Province (110+).

2.2 Certifications

All products have obtained FDA/CE/ISO 13485 certifications, meeting international quality and safety standards for global market access.