1.APIS
1.1 Oncology
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Doxorubicin | Used for solid tumors (breast cancer, lung cancer) and hematologic malignancies; controls tumor progression and metastasis-related complications (e.g., pain, organ compression). |
| Epirubicin | Treats breast cancer, gastric cancer, colorectal cancer; relieves bleeding, obstruction, and other complications from tumor invasion. |
| Idarubicin | Used for acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL); improves anemia, bleeding, infection, and other complications from leukemic cell infiltration. |
| Pirarubicin | Targets breast cancer, bladder cancer, ovarian cancer; controls tumor growth to reduce local compression and metastasis-related complications. |
| Daunorubicin | Mainly treats acute leukemia; alleviates myelosuppression-related complications (e.g., infection, bleeding) from leukemic cell proliferation. |
| Bleomycin | Used for lymphoma, testicular cancer, lung cancer; treats tumors and prevents metastasis-related complications (e.g., pleural effusion). |
| Mitomycin | Treats solid tumors (gastric cancer, lung cancer); controls tumor progression to reduce obstruction, bleeding, and other complications. |
| Dactinomycin | Used for pediatric rhabdomyosarcoma, choriocarcinoma; relieves local pain, tissue damage, and other complications from tumor invasion. |
| Cytarabine | Mainly treats acute leukemia; improves myelosuppression-related complications (e.g., infection, anemia) by inhibiting leukemic cell proliferation. |
| Cyclophosphamide | Used for lymphoma, breast cancer, ovarian cancer; controls tumor growth and metastasis to reduce pain, compression, and other tumor-related complications. |
| Cladribine | Treats hairy cell leukemia, chronic lymphocytic leukemia (CLL); improves immunosuppression, anemia, and other complications from leukemic cell infiltration. |
| Fludarabine | Used for CLL, non-Hodgkin lymphoma; relieves myelosuppression, immunodeficiency, and other tumor-related complications. |
| Anastrozole | Endocrine therapy for postmenopausal breast cancer; inhibits tumor growth and reduces recurrence/metastasis-related complications (e.g., bone metastasis pain). |
| Letrozole | Adjuvant therapy for postmenopausal breast cancer, ovarian cancer; controls tumor progression to prevent organ damage from metastasis. |
| Bicalutamide | Endocrine therapy for prostate cancer; inhibits tumor growth and relieves frequent urination, dysuria, bone metastasis pain, and other complications. |
| Everolimus | Used for advanced renal cell carcinoma, breast cancer, pancreatic cancer; controls progression by inhibiting tumor angiogenesis to reduce metastasis-related complications. |
1.2 Anti-infectives
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Daptomycin | Treats infections (skin/soft tissue infections, sepsis, pneumonia) caused by Staphylococcus aureus (including MRSA); relieves fever, inflammation, and other infection-related complications. |
| Micafungin | Targets fungal infections (sepsis, pneumonia, intra-abdominal infections) caused by Candida spp.; controls infection to improve fever, organ dysfunction, and other complications. |
| Tigecycline | Treats complicated infections (intra-abdominal infections, pneumonia) caused by multidrug-resistant bacteria; relieves high fever, inflammatory response, and other infection-related complications. |
| Teicoplanin | Used for Gram-positive bacterial infections (e.g., Staphylococcus, Streptococcus) causing sepsis, pneumonia; controls infection to reduce fever, tissue damage, and other complications. |
| Linezolid | Treats infections (pneumonia, skin/soft tissue infections) caused by vancomycin-resistant Enterococcus (VRE) and MRSA; relieves fever, inflammation, and other infection-related complications. |
| Meropenem | Broad-spectrum carbapenem for severe bacterial infections (sepsis, pneumonia, urinary tract infections); controls infection to improve organ dysfunction and other complications. |
| Imipenem + Cilastatin | Treats severe infections (intra-abdominal infections, sepsis) caused by multidrug-resistant bacteria; relieves high fever, shock, and other infection-related complications. |
| Favipiravir | Used for influenza virus infections (influenza A/B); inhibits viral replication to relieve fever, cough, dyspnea, and other complications. |
1.3 Cardiovascular
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Adenosine | Treats paroxysmal supraventricular tachycardia; rapidly restores normal rhythm to relieve palpitations, chest tightness, dizziness, and other complications. |
| Pravastatin | Regulates lipid levels (lowers cholesterol); prevents atherosclerosis-related complications (e.g., coronary artery disease, cerebral infarction, peripheral vascular disease). |
| Simvastatin | Lipid-lowering therapy; reduces atherosclerotic plaque formation to prevent myocardial infarction, stroke, and other cardiovascular/cerebrovascular complications. |
| Fluvastatin | Regulates lipid levels for hypercholesterolemia; prevents atherosclerosis-related complications (e.g., coronary artery disease, cerebral infarction). |
| Lovastatin | Lipid-lowering therapy; reduces cholesterol and triglycerides to prevent myocardial infarction, stroke, and other cardiovascular/cerebrovascular complications. |
| Ticagrelor | Antiplatelet agent for acute coronary syndrome (e.g., myocardial infarction); prevents thrombosis-related complications (e.g., reinfarction, stroke). |
| Apixaban | Oral anticoagulant; prevents stroke in patients with non-valvular atrial fibrillation, and thrombus-related complications (e.g., deep vein thrombosis, pulmonary embolism). |
1.4 Other
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Orlistat | Treats obesity; reduces fat absorption to control weight and prevent obesity-related complications (e.g., type 2 diabetes, hypertension, hyperlipidemia). |
| Acarbose | Treats type 2 diabetes; inhibits carbohydrate absorption to lower blood glucose and prevent diabetes-related complications (e.g., nephropathy, retinopathy, neuropathy). |
| Glutathione | Used for drug-induced liver injury, alcoholic liver injury; protects hepatocytes and relieves liver dysfunction-related complications (e.g., jaundice, ascites). |
| Ademetionine 1,4-Butanedisulfonate | Treats cholestatic liver disease; improves jaundice, pruritus, and other complications from impaired bile excretion. |
| Tacrolimus | Immunosuppressant for organ transplantation (liver, kidney, heart); prevents transplant rejection-related complications (e.g., graft failure). |
| Sirolimus | Immunosuppressant for organ transplantation; prevents rejection and treats complications related to vascular smooth muscle proliferation (e.g., in-stent restenosis). |
| Mycophenolate Mofetil | Immunosuppressant for organ transplantation; prevents rejection and reduces graft dysfunction-related complications. |
| Lurasidone Hydrochloride | Treats schizophrenia, bipolar disorder; relieves hallucinations, delusions, mood instability, and improves social dysfunction-related complications. |
| Donepezil Hydrochloride | Treats Alzheimer's disease; improves cognitive impairment (e.g., memory loss, slowed thinking) and delays functional decline-related complications. |
1.5 Veterinary
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Doramectin | Used for internal/external parasitic infections (mites, nematodes) in livestock (cattle, sheep, pigs); relieves emaciation, diarrhea, skin inflammation, and other parasite-related complications. |
| Eprinomectin | Parasite control in livestock (cattle, sheep); manages growth retardation, pruritus, and other complications from mite/nematode infections. |
| Fipronil | Controls external parasites (fleas, ticks) in pets (cats, dogs); relieves pruritus, inflammation, and other complications from parasite bites. |
| Ivermectin | Treats internal/external parasitic infections (nematodes, mites) in livestock/pets; improves malnutrition, skin damage, and other parasite-related complications. |
| Milbemycin Oxime | Controls intestinal nematodes/external parasites in pets; prevents diarrhea, emaciation, and other parasite-related complications. |
| Moxidectin | Treats nematode/mite infections in livestock (cattle, sheep, horses); relieves growth inhibition, skin inflammation, and other parasite-related complications. |
| Praziquantel | Treats schistosome/tapeworm infections in livestock/pets; controls infections to improve digestive dysfunction, emaciation, and other complications. |
| Selamectin | Controls external parasites (fleas, ticks) and internal nematodes in pets (cats, dogs); relieves pruritus, diarrhea, and other parasite-related complications. |
| Tulathromycin | Treats respiratory bacterial infections (e.g., pasteurellosis, mycoplasmosis) in livestock (cattle, pigs); relieves cough, dyspnea, fever, and other complications. |
2.FDF
2.1 Oncology & Immunosuppressants
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Anastrozole Tablets | Manages bone metastasis pain and disease progression complications in postmenopausal breast cancer. |
| Bicalutamide Tablets | Relieves urinary obstruction, bone metastasis pain, and progression-related symptoms in prostate cancer. |
| Bleomycin Hydrochloride for Injection | Controls pleural effusion and tissue damage complications from lymphoma, testicular cancer, etc. |
| Cladribine for Injection (USP Standard) | Alleviates immunodeficiency, anemia, and infection complications in hairy cell leukemia/CLL. |
| Cytarabine Hydrochloride for Injection | Improves myelosuppression (infection, bleeding) in acute leukemias. |
| Dactinomycin D for Injection (USP Standard) | Reduces local pain and tissue invasion complications in pediatric rhabdomyosarcoma, choriocarcinoma. |
| Daunorubicin Hydrochloride for Injection (USP Standard) | Relieves myelosuppression (infection, bleeding) in acute leukemias. |
| Epirubicin for Injection | Mitigates bleeding, obstruction, and local invasion complications in breast/gastric/colorectal cancer. |
| Fludarabine Phosphate for Injection (USP Standard) | Alleviates immunodeficiency and myelosuppression in CLL/non-Hodgkin lymphoma. |
| Gemcitabine Hydrochloride for Injection | Manages disease progression and organ dysfunction complications in pancreatic/lung/breast cancer. |
| Idarubicin Hydrochloride for Injection | Improves anemia, bleeding, and infection complications in acute leukemias. |
| Letrozole Tablets | Prevents bone metastasis and organ damage complications in postmenopausal breast/ovarian cancer. |
| Mitomycin for Injection | Reduces obstruction and bleeding complications in gastric/lung/colorectal cancer. |
| Pirarubicin Hydrochloride for Injection | Controls local compression and metastasis-related pain in breast/bladder/ovarian cancer. |
| Tacrolimus Capsules | Prevents graft rejection and organ failure complications in solid organ/HSCT transplants. |
2.2 Anti-infectives
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Daptomycin for Injection (USP Standard) | Relieves fever, inflammation, and organ damage in MRSA-related skin infections/sepsis/pneumonia. |
| Favipiravir Tablets | Alleviates fever, cough, and dyspnea complications in influenza A/B infections. |
| Imipenem + Cilastatin for Injection | Controls high fever, shock, and organ dysfunction in multidrug-resistant bacterial infections. |
| Isepamicin Sulfate for Injection | Relieves fever and tissue inflammation in Gram-negative bacterial infections (UTIs, sepsis). |
| Linezolid Tablets | Reduces fever and inflammation in VRE/MRSA-related pneumonia/skin infections. |
| Meropenem for Injection | Manages organ dysfunction in severe bacterial infections (sepsis, pneumonia, UTIs). |
| Micafungin for Injection (USP Standard) | Alleviates fever and organ damage in Candida-related sepsis/pneumonia/intra-abdominal infections. |
| Moxifloxacin Hydrochloride Tablets | Relieves fever, cough, and inflammation in respiratory/urinary tract bacterial infections. |
| Teicoplanin for Injection | Controls fever and tissue damage in Gram-positive bacterial infections (sepsis, pneumonia). |
| Tigecycline for Injection | Reduces high fever and inflammatory response in multidrug-resistant bacterial infections. |
| Vancomycin Hydrochloride for Injection | Manages fever and organ damage in Gram-positive bacterial infections (sepsis, endocarditis). |
2.3 Cardiovascular
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Butibufen Tablets | Relieves pain and inflammation in cardiovascular-related musculoskeletal complications. |
| Irbesartan Tablets (USP Standard) | Prevents stroke, myocardial infarction, and renal damage in hypertension/heart failure. |
| Ticagrelor Tablets (USP Standard) | Reduces reinfarction and stroke complications in acute coronary syndrome. |
2.4 Gastrointestinal & Metabolic
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Acarbose Tablets | Prevents nephropathy, retinopathy, and neuropathy in type 2 diabetes. |
| Ademetionine 1,4-Butanedисulfonate Enteric-coated Tablets | Relieves jaundice and pruritus in cholestatic liver disease. |
| Ademetionine 1,4-Butanedисulfonate for Injection | Alleviates jaundice and liver dysfunction in cholestatic liver disease. |
| Fluvastatin Sodium Capsules | Prevents atherosclerosis-related myocardial infarction and stroke. |
| Orlistat Tablets | Reduces obesity-related type 2 diabetes, hypertension, and hyperlipidemia. |
| Pravastatin Sodium Tablets | Prevents myocardial infarction and stroke via lipid-lowering (atherosclerosis management). |
| Rosiglitazone Hydrochloride Tablets | Manages insulin resistance and diabetes-related vascular complications. |
| Rosuvastatin Calcium Tablets | Prevents atherosclerosis-related myocardial infarction, stroke, and peripheral vascular disease. |
| Glutathione for Injection | Relieves jaundice and ascites in drug/alcohol-induced liver injury. |
| Cycloserine Capsules | Manages neurological complications (seizures, depression) in tuberculosis treatment. |
2.5 Others
| Drug Name | Core Therapeutic Indications (Including Complication Management) |
|---|---|
| Glucosamine Sulfate Capsules | Relieves joint pain and inflammation in osteoarthritis. |
| Lurasidone Hydrochloride Tablets | Alleviates hallucinations, delusions, and social dysfunction in schizophrenia/bipolar disorder. |
| Solifenacin Succinate Tablets | Reduces urinary frequency and urgency complications in overactive bladder. |